Body · 12 episodes
Fitness & Exercise for entrepreneurs
Nobody on this show argues that fitness is optional for entrepreneurs. What they disagree on is which lever matters most. Some guests point to muscle and strength as the real predictor of long-term function, others to VO2 max and cardiovascular capacity, others to sleep, and still others to nervous system regulation through breath and cold exposure. Nobody thinks diet alone explains outcomes, and several explicitly push back on that assumption. The common thread isn't a single practice, it's that physical inputs are treated as direct levers on decision-making, energy, and resilience, not as separate from the business.
The other consistent thread is that consistency beats intensity, and environment beats willpower. Compound interest, not heroics, is the metaphor that keeps recurring: daily movement, a repeatable diet, structured sleep, and small hourly resets do more than occasional extreme efforts. Several guests also warn that looking fit can hide real problems, biomarkers, cortisol, visceral fat, cholesterol, that outward leanness doesn't reveal. And a few push past physical mechanics entirely into identity: what happens when the discipline that built the business becomes the thing burning the founder out.
Where it gets genuinely useful is in the specifics. A breath-hold test as a stress gauge. Blood flow restriction training to build muscle without loading joints. DEXA scans over BMI. Air squats every hour instead of one long gym session. This page collects the mechanisms, not just the encouragement to 'take care of yourself.'
What holds across every conversation
- •Test a breath hold or grip strength check as a quick, free readout of nervous system stress and recovery capacity.
- •Move every hour, not just once a day; research on hourly air squats shows near-equivalent benefit to a single 30-minute session.
- •Get a DEXA scan and basic blood panel before trusting body fat percentage or how you look in the mirror.
- •Build hormetic stress (cold, breath holds, sauna) deliberately into your week to train tolerance for high-stakes business stress, not just physical stress.
- •Design your environment (pre-planned meals, removed junk food, fixed routines) instead of relying on willpower, since partial consistency still produces statistically real results.
- •Prioritize muscle strength and VO2 max training now; both are among the strongest predictors of independence and healthspan decades out.
Strength, muscle, and staying upright
Multiple guests independently name muscle strength, not cardio or diet, as the strongest predictor of long-term independence and longevity.
“The number one predictor of longevity is muscle strength and partly because you keep your balance, you don't fall over, everything stays upright.”
Dr. Mihir Patel: Muscle Strength, Longevity & Joint Health · 44:03· listen →
“Hip fractures, if you look at the medical studies out there, it's a 90% mortality rate at the end of 1 year.”
Dr. Mihir Patel: Muscle Strength, Longevity & Joint Health · 5:45· listen →
“When you get older, it's much harder to build muscle. So if you have a younger audience, go to the gym. And I see it a lot when you go to the gym, you see much less women, especially in our age, lifting weight. And it is important.”
Biomarkers, Biological Age & the Science of Healthspan · 25:24· listen →
“Blood flow restriction is— think in simple terms, think a tourniquet. You put a tourniquet on your leg, you work out, and you get a burn a lot faster than you would otherwise because you've cut the blood supply off. But it's measured, it's calculated, and it lets you build the muscle but without the extra weight.”
Dr. Mihir Patel: Muscle Strength, Longevity & Joint Health · 43:30· listen →
“The difference in literally the years you will live, but also the quality of those years. They can actually predict based on your VO2 max when you can no longer live independently and you're going to have to have somebody help.”
Fitness for Busy Entrepreneurs with Eric D'Agati · 15:27· listen →
Consistency over intensity
Fitness works like compound interest, and the data shows partial adherence still moves the needle, which removes the excuse that all-or-nothing routines are required.
“It's not like getting your haircut where you do get it done and you can come back 2 weeks later. It's cumulative. And that's what most people don't get. They think of it in isolation and in a silo.”
Fitness for Busy Entrepreneurs with Eric D'Agati · 3:26· listen →
“The research shows that doing as little as some air squats every single hour has almost the same impact as if you were to do 30 minutes on the bike at the end of the day.”
Fitness for Busy Entrepreneurs with Eric D'Agati · 4:46· listen →
“What we saw was, as you'd expect, people who were more consistent saw improved results. But the group that had 29 to 50% consistency still saw statistically significant improvements.”
The ROI of Health and Fitness for Entrepreneurs · 23:36· listen →
“If I don't move every day in one way or another, things get bad, so I always make that a huge priority.”
Alex Canavan: Building Community Without Burnout · 14:12· listen →
“I eat the same thing every day. For the most part, like down to a T. And that might sound like a little much, but honestly, it's made my life significantly easier and less stressful.”
Alex Canavan: Building Community Without Burnout · 19:55· listen →
Breath, nervous system, and hormetic stress
Deliberate breath holds, cold, and other controlled stressors train the amygdala and endocannabinoid system, building the same adaptive capacity used to handle high-stakes pitches and decisions.
“The idea of hormetic stress is consciously and intentionally inducing stressors in order to make adaptations. If you think about it in simple terms, it's what happens when you really strength train. When you lift weights, you're inducing a stressor to the muscles and to the fascia. There's a bit of inflammation because of that, and then you get stronger.”
Reset Your Nervous System for Peak Performance · 23:27· listen →
“3 minutes of deep breathing, strong, and you have to focus on it a bit, it can't be very passive, followed by a maximal voluntary breath hold increased circulating human growth hormone in the blood by up to 550% a half hour after that was done.”
Reset Your Nervous System for Peak Performance · 37:45· listen →
“We have nociceptors that are threat receptors. Touch a hot pan, threat receptors take the information, the threatening heat, danger. That sends the signal afferently to the brain, and really through the spinal cord and the brainstem. The brain then makes processes and makes a decision on the pain perception to come back out.”
Reset Your Nervous System for Peak Performance · 8:44· listen →
“The reason we don't take breathwork seriously is because we call it breathwork when in fact it's respiratory physiology. And if we could just understand that it's respiratory physiology and this is real and not woo, people would get more out of it perhaps.”
Reset Your Nervous System for Peak Performance · 45:27· listen →
“Most people unfortunately kind of are living at the simmering 7, especially entrepreneurs. They're constantly at this simmering 7 or 8. They never really get to 10, and they also never get down to 0, and so they kind of burn out because they're revving at this high RPMs.”
Fitness for Busy Entrepreneurs with Eric D'Agati · 21:03· listen →
Looking fit isn't the same as being healthy
Lean bodies still carry hidden risk. Biomarkers, glucose monitors, and DEXA scans expose problems that mirrors and scales don't.
“I was sitting maybe at 11, 12% body fat, which is by all accounts relative to the regular population, very, very lean. But I still had high cholesterol and started to do some more work there and realized this runs in my family.”
The ROI of Health and Fitness for Entrepreneurs · 9:46· listen →
“I would see these blips throughout the day in the glucose monitor that were in the normal range, but that it wasn't associated with food... there are cortisol pops to increase glucose... So it wasn't that I am super chill... I was completely unaware of the physical impact that was happening on my body.”
The ROI of Health and Fitness for Entrepreneurs · 12:40· listen →
“You have 2 women who have 26% body fat. One might have 1 pound of visceral fat, one might have 3 pounds. They're the same weight, the same percent body fat, but the amount of visceral fat they have is dramatically different.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 18:09· listen →
“The 2 things I think are most foundational are blood work and DEXA scan... they're not expensive, it's like $50 to $100.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 38:55· listen →
“And by the way, bad night's sleep have a lot of an effect the day after. You make a bad decision. You are more grumpy. You have a higher chance to have higher rates and high glucose and your testosterone usually is lower. And so you are also, your cortisol, your stress is higher. You are more prone to get injured.”
Biomarkers, Biological Age & the Science of Healthspan · 32:58· listen →
Environment design beats willpower
Guests converge on the idea that removing friction and pre-deciding routines produces better outcomes than relying on discipline alone.
“Environment drives behavior. And is the biggest influencer on behavior that people don't talk about more than anything else. Myself, people say, oh, you must be so disciplined. You must have high willpower. I have neither, nor do I want either.”
The ROI of Health and Fitness for Entrepreneurs · 26:38· listen →
“The very first thing is finding your why, your purpose. for doing it. That's the very first thing. And having that and sticking that somewhere that you can see all the time, because that is the core behind what's going to get you into these behaviors.”
The ROI of Health and Fitness for Entrepreneurs · 36:12· listen →
“Definitely, the goal that helps with hard choices has to be really the big goal. We want big things. And even if they take 5 years, they can help us with those hard choices now and develop this microprogressive system to get there.”
Jerzy Gregorek: Hard Choices, Easy Life Explained · 18:45· listen →
“As a leader, as an entrepreneur, you're constantly having to make quick decisions all day long. You're having to solve everyone's problems. And it's just nice to have one less problem to solve.”
Alex Canavan: Building Community Without Burnout · 23:28· listen →
Rest, recovery, and not burning out the leader
The body that builds the company also has to survive it. Several guests learned this the hard way, through burnout, forced exits, or physical breakdown.
“I had shown up and fixed this exact problem I was having for so long here in Central New York, but I fixed it for everybody else. And I was very much building, the founder of a startup company, and I was not prioritizing building a support system for myself and making sure that my own social-emotional needs were being met by the people around me.”
Alex Canavan: Building Community Without Burnout · 5:46· listen →
“I ended up getting to the point where I said, this is pretty ironic. I'm going to school and learning how to teach people how to recover and be healthy. Yet I am probably at the most unhealthy point in my life.”
Dr. Spencer Lalk: Storytelling, Health & Startup Growth · 8:31· listen →
“When I take calls now, I pop in AirPods and I walk while I talk. It's actually gonna provide some clarity in your thought and open up some space in your brain to continue to be productive and creative, to drive innovation in your business.”
Dr. Spencer Lalk: Storytelling, Health & Startup Growth · 27:23· listen →
“As a human, your number one job in life is to be a professional sleeper... if you can do that, then the idea is you go to bed on time and you wake up when you're done, the same way you go to work on time and you leave work when you're done.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 13:43· listen →
“So there's a lot that goes into really preserving that energy when I'm not, quote unquote, out in public.”
Ashley Black: Necessity, Near-Death & High Vibration Living · 10:09· listen →
The companion guide
Reading about fitness & exercise is one thing. Changing it is another.
John’s companion guide turns what these conversations cover into something you can actually work through.
More moments worth hearing
Everything else these conversations turned up on this subject.
“The beauty of events is that if your guests didn't plan the event, they don't know what's wrong. So, if something goes wrong, just cover it up with a smile and ask for forgiveness if you have to. At that point, there's nothing you can do.”
Alex Canavan: Building Community Without Burnout · 10:19
“There's just something so therapeutic about getting your thoughts out on paper and just leaving them there, you know, and not letting yourself ruminate on anything. It's been huge for me.”
Alex Canavan: Building Community Without Burnout · 30:07
“None of it matters if the relationships in our lives don't feel good. So that's something that I'm very proud of, that I can say that I've made that a priority.”
Alex Canavan: Building Community Without Burnout · 35:19
“Because hard choices then are happening when discomfort happens, some self-control happens, and we are more aligned with the long-term vision for ourselves and wait for the reward. It's really hard to do it, hard to save money, let's say, and put the money into retirement and wait and have that vision and connection all the time to the future.”
Jerzy Gregorek: Hard Choices, Easy Life Explained · 0:31
“My purpose was to find money to drink, right? If I could find money and the money I could find with other people, somebody was paid, somebody had some things, and we always found these people who had money.”
Jerzy Gregorek: Hard Choices, Easy Life Explained · 6:36
“So we said no, the strike happened. I was one of the leaders of the strike. And after 10 days, helicopter landed on the room or the roof, and then tanks moved in. And they took us out.”
Jerzy Gregorek: Hard Choices, Easy Life Explained · 10:14
“So that is the same thing. We go to the gym and we spend in the gym 5 years or 10 years, and we are the same or worse. A lot of people have experienced like that. Or you go to the gym and have the plan, have the strategies. You still go to the gym like others. You do the training.”
Jerzy Gregorek: Hard Choices, Easy Life Explained · 20:36
“It's the same thing. You're already signaling to your brain in a very hardline way how you want to go forward as you get up.”
Reset Your Nervous System for Peak Performance · 43:04
“You should only feel bad about selling your product if it's not, if it's something that you don't believe in. So if you don't believe in it, then yeah, you should feel bad about selling it. But if you're producing and creating something that you feel like is genuinely gonna make the world a better place and help them, then feel good about it.”
Dr. Spencer Lalk: Storytelling, Health & Startup Growth · 20:19
“You'd rather have a small audience that actually cares about the things that you wanna offer rather than an incredibly large audience that has a diverse interest set and not actually gonna become buyers.”
Dr. Spencer Lalk: Storytelling, Health & Startup Growth · 25:09
“We are often oftentimes sitting in a prison cell and we're looking through the window, looking up at the sky. But all we need to do is turn around and realize that the door is already open.”
Dr. Spencer Lalk: Storytelling, Health & Startup Growth · 32:54
“Longevity, you can look at it at a lifespan, basically the length of time that you live from birth to death. And there is what we call the healthspan, how long that you live in good health. So I assume that everyone wants to live better longer.”
Biomarkers, Biological Age & the Science of Healthspan · 1:16
“Yeah, it's not easy, but I don't think that anything is easy and you need to take some risks. So I took a big risk that I assumed that other people won't take. So I think that that's a big difference between entrepreneur and non-entrepreneur. It's someone that takes risks and they're willing to take the consequences of that risk.”
Biomarkers, Biological Age & the Science of Healthspan · 4:14
“But again, if you would ask me about caloric restriction 10 years ago, I would be very bullish. Right now I'm a bit less bullish about it because I'm not sure that this is the best intervention, especially in humans.”
Biomarkers, Biological Age & the Science of Healthspan · 12:03
“I'm saying it's less wrong. No, I'm, for example, I'm not drinking alcohol at all. That's the intervention that I decided to do, but that's my decision. Everyone, you know, it's at the end of the day, we need to enjoy life.”
Biomarkers, Biological Age & the Science of Healthspan · 30:21
“And also, it doesn't mean that if you work 15 hours every day, you are more productive. It might be that 8 hours that you are more focused is better than 15 hours that you are less focused. So, don't come say, I'm an entrepreneur, I have to work 15 hours a day. It doesn't— it's not true.”
Biomarkers, Biological Age & the Science of Healthspan · 34:29
“Say 1 drink a day, 7 drinks a week. The general consensus that I can see is that that's probably not like really bad, but it certainly is not better than zero.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 5:05
“There are ways to create that sort of social connection of feeling like you're drinking without actually ingesting much... one of my go-to drinks is bitters and soda.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 8:19
“The number one thing I think that is maybe a misnomer in this space, I think personally, is that diet is 80%, 90%, the most important thing you can focus on... it's not to say diet isn't important because it is, but this sometimes becomes a limiting belief.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 24:45
“If there is a secret to longevity, it's not a secret, it's first your lifestyle. The things that have the most proof are caloric balance, exercise, sleep, aggressive screening. There's no secrets out there.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 27:18
Every episode on fitness & exercise
12 conversations, oldest to newest.
Alex Canavan: Building Community Without Burnout
A dance background instilled discipline, self-accountability, and the ability to perform even when things go wrong, which translates directly into entrepreneurship.
Jerzy Gregorek: Hard Choices, Easy Life Explained
Hard choices produce an easy life through delayed gratification, while easy choices that feel good now often produce a harder life later.
Reset Your Nervous System for Peak Performance
Pain is an output created by the brain's processing of threat signals, not an input from the injured body part, so changing sensory information can change pain perception.
Dr. Spencer Lalk: Storytelling, Health & Startup Growth
Storytelling and emotional connection drive better patient and customer decisions than raw data or anatomy facts.
Biomarkers, Biological Age & the Science of Healthspan
Longevity should be measured by healthspan, the years lived in good health, not just raw lifespan.
Longevity As a Competitive Edge: Jesse Levey on Health Strategy
Most longevity advice is overly individualized or dogmatic, but reducing alcohol and optimizing sleep benefit almost everyone.
Dr. Mihir Patel: Muscle Strength, Longevity & Joint Health
Muscle strength, mobility, and flexibility are the most important factors in preventing orthopedic injuries and staying out of the OR as we age.
Fitness for Busy Entrepreneurs with Eric D'Agati
Physical health works cumulatively like compound interest, not through occasional intense bursts, so consistency beats intensity.
Richard Blank on Phone Communication & Soft Skills
Small talk and genuine curiosity about the person on the other end of a call disarms defensiveness faster than any sales pitch.
Bart Foster: Business Outside and the Power of Nature
Conducting business outdoors and walking shoulder-to-shoulder makes people calmer, more authentic, and more vulnerable, leading to deeper connections than coffee or lunch meetings.
The ROI of Health and Fitness for Entrepreneurs
Exercise and nutrition act like a natural 'smart drug,' boosting decision-making, emotional regulation, and cognitive flexibility for leaders.
Ashley Black: Necessity, Near-Death & High Vibration Living
Ashley Black's chronic childhood illness and a near-fatal infection directly led her to invent the Fascia Blaster and build a $200 million company.