Longevity & Healthspan for entrepreneurs

“Longevity, you can look at it at a lifespan, basically the length of time that you live from birth to death. And there is what we call the healthspan, how long that you live in good health. So I assume that everyone wants to live better longer.”

Biomarkers, Biological Age & the Science of Healthspan · 1:16· listen →

“I always look for what I call the 4 Horsemen of executive burnout. So the first one is sleep latency extending beyond 25 minutes... The second one is cortisol staying elevated after 10... There's also how your fasting glucose is going to vary during the day... The last thing is your heart rate variability when you sleep.”

Dr. Emilie Laplagne: Functional Medicine for Entrepreneurs · 16:23· listen →

“The 2 things I think are most foundational are blood work and DEXA scan... they're not expensive, it's like $50 to $100.”

Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 38:55· listen →

“My fear with a biological clock is that you're doing things that may be making it look younger on the test that doesn't actually make you younger in reality.”

Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 33:29· listen →

“You know, depending on the statistic you look at, maybe 10% of, you know, our healthspan and lifespan is genetically determined, maybe 10%, perhaps less than that. So yeah, 90% of how well we live is on us.”

Reverse Biological Age: Dr. Kara Fitzgerald on Diet & Sleep · 15:27· listen →

“The number one predictor of longevity is muscle strength and partly because you keep your balance, you don't fall over, everything stays upright.”

Dr. Mihir Patel: Muscle Strength, Longevity & Joint Health · 44:03· listen →

“Hip fractures, if you look at the medical studies out there, it's a 90% mortality rate at the end of 1 year.”

Dr. Mihir Patel: Muscle Strength, Longevity & Joint Health · 5:45· listen →

“I used to tell patients it's kind of like a toilet bowl. You're spinning up on top and then all of a sudden you spin down into the gutter. And so here you're breaking that cycle and you're out of that toilet bowl at the end of the day. And so you can get stronger.”

Dr. Mihir Patel: Muscle Strength, Longevity & Joint Health · 16:10· listen →

“When you get older, it's much harder to build muscle. So if you have a younger audience, go to the gym. And I see it a lot when you go to the gym, you see much less women, especially in our age, lifting weight. And it is important.”

Biomarkers, Biological Age & the Science of Healthspan · 25:24· listen →

“You have 2 women who have 26% body fat. One might have 1 pound of visceral fat, one might have 3 pounds. They're the same weight, the same percent body fat, but the amount of visceral fat they have is dramatically different.”

Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 18:09· listen →

“It's the Sleep Foundation that has a study that says that every single night of poor sleep can reduce cognitive performance the next day by 25%. And it's the equivalent of a blood alcohol level of 0.05%.”

Dr. Emilie Laplagne: Functional Medicine for Entrepreneurs · 34:38· listen →

“And by the way, bad night's sleep have a lot of an effect the day after. You make a bad decision. You are more grumpy. You have a higher chance to have higher rates and high glucose and your testosterone usually is lower. And so you are also, your cortisol, your stress is higher. You are more prone to get injured.”

Biomarkers, Biological Age & the Science of Healthspan · 32:58· listen →

“One of the most extraordinary learnings for me in my journey in this science was how potent stress is as a pro-aging phenomenon. It may be the most— I've described it before as just like gasoline on the fire of aging.”

Reverse Biological Age: Dr. Kara Fitzgerald on Diet & Sleep · 19:45· listen →

“You'll notice that your resting heart rate— it's measurable— your resting heart rate will drop by about 10 points after doing 2, 3 minutes of this breathing, which is like amazing if you think about it. It's faster than taking a Xanax.”

Dr. Mao Shing Ni on Energy, Qi, and Longevity Secrets · 33:53· listen →

“As a human, your number one job in life is to be a professional sleeper... if you can do that, then the idea is you go to bed on time and you wake up when you're done, the same way you go to work on time and you leave work when you're done.”

Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 13:43· listen →

“Well, the first thing is you've got to stop putting it in the body. Yeah. The body will do it. With enough time, the body will just do it. You don't have to do anything. If you get out of the moldy environment, you don't have to do a thing.”

The EDGE Framework for Longevity With Sandy Martin · 19:58· listen →

“The part of my brain that governed tasks and anything with a sequence, so including a sentence, speaking was difficult because I couldn't find the words in order. And then I couldn't read a spreadsheet and I was just stuck. I was buffering every single thing I did.”

The EDGE Framework for Longevity With Sandy Martin · 9:57· listen →

“I think that that's what most people don't understand about the psychophysiological nature of being human, is that there are all kinds of microbes and organisms and hormones and molecules that affect our thoughts, but we're so egocentric. That we think it's us.”

The EDGE Framework for Longevity With Sandy Martin · 17:29· listen →

“A very easy scientific test you can do at home is put the powder on a plate and add some iodine to it. And if that powder turns black, purple-black, then that shows up for starch.”

Julian Mitchell on Functional Mushrooms & Biohacking · 8:16· listen →

“When you think you're buying a lion's mane capsule or powder, you're actually buying 68% of blended rice, blended grain. So that's almost criminal and it's really bad for the industry.”

Julian Mitchell on Functional Mushrooms & Biohacking · 22:52· listen →

“But again, if you would ask me about caloric restriction 10 years ago, I would be very bullish. Right now I'm a bit less bullish about it because I'm not sure that this is the best intervention, especially in humans.”

Biomarkers, Biological Age & the Science of Healthspan · 12:03· listen →

“The number one thing I think that is maybe a misnomer in this space, I think personally, is that diet is 80%, 90%, the most important thing you can focus on... it's not to say diet isn't important because it is, but this sometimes becomes a limiting belief.”

Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 24:45· listen →

“We could see that our research participants in 8 weeks' time got over 3 years younger using the clock as compared to the control group.”

Reverse Biological Age: Dr. Kara Fitzgerald on Diet & Sleep · 11:02· listen →

“Exercise is a ridiculously potent DNA methylation, you know, gene regulator. It's incredible. It looks like kale. It really does.”

Reverse Biological Age: Dr. Kara Fitzgerald on Diet & Sleep · 26:13· listen →

“Natural means I go out and I pick the apple off the tree and I eat it. That is the only way food is natural. And so in an ideal world, we would eat that way, and what I suggest is that people eat as much fruits and vegetables and things that are naturally, rather than being processed, try to get your diet as much as you can in that way.”

Dr. Lynn Anderson: Proactive Aging & Naturopathic Health · 10:17· listen →

“And my patients who put their head in the sand and think, oh, if I just work out enough, I'm going to be able to not grow old and avoid all this stuff. I'll never be sick. I'll live forever. I mean, that's toxic right there.”

Joyspan Over Lifespan: Dr. Kerry Burnight on Aging Well · 2:40· listen →

“So when you expect what I call the decline aging mindset, which has a beautiful acronym of DAMN, when you think, damn, I'm getting older, everything's going to be worse. I'm going to be less relevant. I'm going to be less quick. I'm going to be less effective. I'm going to be less attractive. When you believe that, that is really— that comes to pass.”

Joyspan Over Lifespan: Dr. Kerry Burnight on Aging Well · 15:00· listen →

“Every one of my patients who has maintained connection in longevity has been the proactive one. Every time I have somebody come in and say, nobody reaches out to me, I don't have anyone, I'm entirely alone, we then say, okay, now tell me about your habits of how you are reaching out to people? And invariably they go, well, nobody reaches out to me. I'm like, exactly.”

Joyspan Over Lifespan: Dr. Kerry Burnight on Aging Well · 20:10· listen →

“Yeah. First of all, if you think about it, if you're out there building a business, you're scaling up, you're doing everything you can. Ultimately, yes, you have a company, you have people that are doing the work, but you're the leader. And leaders spend a lot of energy driving their vision and realization of their vision. So a lot of people think like their greatest assets, it's intelligence, which is true. Their capital, yes, and strategy, no question. But really, your true currency is energy.”

Dr. Mao Shing Ni on Energy, Qi, and Longevity Secrets · 15:35· listen →

“Why win one prize and then lose 3 others, whether it's your health, relationships, friendships? I'm more of a pro the balanced entrepreneur, not the extreme entrepreneur that burns other boats that are actually really valuable for a meaningful life.”

Julian Mitchell on Functional Mushrooms & Biohacking · 35:37· listen →

“It's the discipline for the morning routine is easy. The discipline for the evening routine is the one everyone needs to nail.”

Julian Mitchell on Functional Mushrooms & Biohacking · 13:46

“It never makes sense until you look backwards.”

Julian Mitchell on Functional Mushrooms & Biohacking · 28:18

“Business people is that they get a second chance or a third chance and you can reinvent yourself in your 40s and your 50s and your 60s. As an athlete, you have a finite window.”

Julian Mitchell on Functional Mushrooms & Biohacking · 38:54

“Provide the master chef with the ingredients and let the master chef do the cooking.”

Julian Mitchell on Functional Mushrooms & Biohacking · 43:06

“Not many people know that, but Ozempic, for example, GLP-1s, they're actually delayed by several decades. The first approval for it was in 2003. And that was for diabetes and later it was used off-label for other things, which is a whole story on its own. And the science is even older. The first trials happened in the 1980s.”

Niklas Anzinger: Building Prospera & Infinita City · 7:48

“The mini-circle gene therapy, for example, costs $25,000. But it's actually really cheap in relative terms because most gene therapies in the United States cost upwards of $500,000 or $1 million, right?”

Niklas Anzinger: Building Prospera & Infinita City · 16:22

“So Khloe Kardashian has been treated with a gene therapy that started in Prospera, right? So when you're a company that starts there, you can have different options in terms of distribution and go-to-market.”

Niklas Anzinger: Building Prospera & Infinita City · 38:01

“Be courageous, right? Be bold, right? You know, take, do not be afraid to take big shots in life and fail in the process, right? And then try again.”

Niklas Anzinger: Building Prospera & Infinita City · 44:33

“I felt like I was just putting a bandaid on a cancer basically.”

Dr. Emilie Laplagne: Functional Medicine for Entrepreneurs · 2:14

“There was a study that showed that only 12% of Americans are actually metabolically healthy on all measures.”

Dr. Emilie Laplagne: Functional Medicine for Entrepreneurs · 20:22

“Alcohol is the worst... it's still a poison, you know. It's terrible for your liver. It's just a poison for your arteries as well. And more than that, you know, it also really messes up your sleep.”

Dr. Emilie Laplagne: Functional Medicine for Entrepreneurs · 28:12

“70% of chronic diseases are lifestyle-related and therefore preventable today.”

Dr. Emilie Laplagne: Functional Medicine for Entrepreneurs · 42:50

“McKinsey conducted a study with leaders and they showed that the leaders who prioritize their own wellbeing inspired 90% higher employee satisfaction and 70% lower burnout rates in their teams.”

Dr. Emilie Laplagne: Functional Medicine for Entrepreneurs · 45:34

“The same thing that would help you in your life between ages 23 and 24 will improve your life between 93 and 94.”

Joyspan Over Lifespan: Dr. Kerry Burnight on Aging Well · 13:54

“Not because it's easy, but because the alternative is worse. Like to get a big whammy of a loss or a diagnosis and not adapt to it and suffer and shake your fist at it. If it worked, I would say go for it. But all I see it bringing is decades of suffering.”

Joyspan Over Lifespan: Dr. Kerry Burnight on Aging Well · 33:20

“I'm grateful for this pillow. I look over, I'm grateful for my husband, grateful for these 3 kids, I'm grateful that I can breathe. I'm, you know, just— and every day you can shake it up or you can do it the same, but it does, it kind of like puts you on a path of saying, I can look at what is wrong or I can look at what is right.”

Joyspan Over Lifespan: Dr. Kerry Burnight on Aging Well · 34:03

“Yeah, it's not easy, but I don't think that anything is easy and you need to take some risks. So I took a big risk that I assumed that other people won't take. So I think that that's a big difference between entrepreneur and non-entrepreneur. It's someone that takes risks and they're willing to take the consequences of that risk.”

Biomarkers, Biological Age & the Science of Healthspan · 4:14

“I'm saying it's less wrong. No, I'm, for example, I'm not drinking alcohol at all. That's the intervention that I decided to do, but that's my decision. Everyone, you know, it's at the end of the day, we need to enjoy life.”

Biomarkers, Biological Age & the Science of Healthspan · 30:21

“And also, it doesn't mean that if you work 15 hours every day, you are more productive. It might be that 8 hours that you are more focused is better than 15 hours that you are less focused. So, don't come say, I'm an entrepreneur, I have to work 15 hours a day. It doesn't— it's not true.”

Biomarkers, Biological Age & the Science of Healthspan · 34:29

“Say 1 drink a day, 7 drinks a week. The general consensus that I can see is that that's probably not like really bad, but it certainly is not better than zero.”

Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 5:05