Body · 9 episodes
Supplements & Functional Mushrooms for entrepreneurs
Ask five guests what to take and you'll get five different answers, but ask what to test first and they converge fast: know what's actually in the product, know what's happening in your body, and fix the environment before you add anything to it. The mushroom and algae conversations get specific about mechanism — lion's mane for neuroinflammation and REM sleep, cordyceps for ATP-based energy, spirulina for mitochondrial fuel, chlorella for binding heavy metals — but every one of them opens with a warning about quality. Most mushroom powders are mostly starch and grain filler. Most fish oil is just borrowed omega-3 the fish got from algae in the first place. Buy the wrong thing and you're paying to be underwhelmed at best.
Where the real disagreement shows up is on emphasis. One camp treats supplementation and functional foods as foundational — chlorella as a daily detox shower, spirulina replacing a fistful of other pills, liquid mushroom extracts as measurably more bioavailable than capsules. Another camp pushes back hard on that framing: diet and supplements get credited with 80-90% of the outcome when the bigger levers are sleep, blood sugar, exercise, and removing toxic exposures you don't know you have. Nobody on this show tells you to skip the basics and go straight to a stack. The functional mushroom guest, the algae founder, and the longevity-data guest all land in the same place from different directions — test before you supplement, and don't let a supplement stand in for a habit.
The environmental and root-cause thread is the one most listeners miss. Mold exposure, glyphosate-treated wheat, plastics, fragrance chemicals, and jaw infections show up as real, diagnosable drivers of fatigue and brain fog that no amount of good supplementation will out-perform. The advice that repeats across guests isn't a brand or a dose — it's sequence. Eliminate what's hurting you, decode what's actually wrong, and only then decide what to add.
What holds across every conversation
- •Run the iodine test on any mushroom powder you own — if it turns purple-black, you're mostly buying starch, not mushroom.
- •Prefer liquid extracts over capsules or powders for mushrooms; bioavailability differences are large enough to matter.
- •Get a DEXA scan and basic bloodwork before assuming a supplement will fix a problem you haven't actually measured.
- •Stop crediting diet with 80-90% of your health outcome — sleep quality and blood sugar balance, especially at breakfast, drive energy and sleep just as much.
- •Before adding anything new, audit for silent drainers first: mold exposure, plastics, fragrance chemicals, glyphosate-heavy grains, and chronic jaw or dental infections.
- •Treat fish oil and multivitamins skeptically — ask where the nutrients actually originate (e.g., fish get omega-3 from algae) before assuming the pill is necessary.
Testing mushroom product quality
Before buying any mushroom supplement, guests describe how to spot filler and why extraction method changes what you're actually getting.
“A very easy scientific test you can do at home is put the powder on a plate and add some iodine to it. And if that powder turns black, purple-black, then that shows up for starch.”
Julian Mitchell on Functional Mushrooms & Biohacking · 8:16· listen →
“When you think you're buying a lion's mane capsule or powder, you're actually buying 68% of blended rice, blended grain. So that's almost criminal and it's really bad for the industry.”
Julian Mitchell on Functional Mushrooms & Biohacking · 22:52· listen →
What each mushroom actually does
Lion's mane, cordyceps, and shilajit serve distinct performance functions — this isn't one supplement doing everything.
“Provide the master chef with the ingredients and let the master chef do the cooking.”
Julian Mitchell on Functional Mushrooms & Biohacking · 43:06· listen →
Algae as complete nutrition and detox
Spirulina and chlorella get treated as two different tools — one for steady cellular energy, the other for pulling toxins out of the bloodstream.
“It is the most nutrient-dense food in the world. NASA feeds it to the astronauts. We have a quote from them saying 1 gram of algae has the same nutrition as 1,000 grams of fruits and vegetables. So 1 to 1,000.”
Spirulina & Chlorella: The Science of Algae Nutrition · 18:40· listen →
“The way I describe it is it's like giving your body a shower from the inside. You take a shower on the outside every morning. Chlorella will pull all the garbage that you've interacted with in the air, your food, your cosmetics, and pull it out.”
Spirulina & Chlorella: The Science of Algae Nutrition · 25:21· listen →
“If someone's stolen your parking spot anywhere, you can't get into your parking spot. It doesn't matter how many signs you put up, but they're there. You gotta get the tow truck or the police to get them out so that you can park in. So, chlorella is the tow truck.”
Spirulina & Chlorella: The Science of Algae Nutrition · 43:39· listen →
“You can get rid of almost all your other supplements. Not all. But your multivitamin, you don't need that. Please stop taking fish oil. Where do you think the fish get the omega-3 from?”
Spirulina & Chlorella: The Science of Algae Nutrition · 46:50· listen →
“In a cancer cell or a senescent cell, the blue pigment, when it's absorbed into the mitochondria, sees that it's in a cancer cell and goes, I'm onto you. And instead of the Ferrari helping move that, move the electrons across, it ejects this thing called cytochrome c, which triggers something called caspases, which triggers something called apoptosis, which is healthy cell death.”
Spirulina & Chlorella: The Science of Algae Nutrition · 36:28· listen →
Why diet and supplements aren't the whole story
Data-driven guests push back on treating nutrition as the dominant lever, arguing sleep, exercise, and screening carry equal or greater weight.
“The number one thing I think that is maybe a misnomer in this space, I think personally, is that diet is 80%, 90%, the most important thing you can focus on... it's not to say diet isn't important because it is, but this sometimes becomes a limiting belief.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 24:45· listen →
“If there is a secret to longevity, it's not a secret, it's first your lifestyle. The things that have the most proof are caloric balance, exercise, sleep, aggressive screening. There's no secrets out there.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 27:18· listen →
“The 2 things I think are most foundational are blood work and DEXA scan... they're not expensive, it's like $50 to $100.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 38:55· listen →
“Blood sugar is the number one thing for quality sleep. Blood sugar balance is the number one thing that will affect quality sleep.”
Gut Health, Real Food & Detox Truths for Entrepreneurs · 26:51· listen →
Fix the environment before you supplement
Toxic mold, household chemicals, and processed food get named as silent drivers of dysfunction that no supplement stack will out-run.
“Well, the first thing is you've got to stop putting it in the body. Yeah. The body will do it. With enough time, the body will just do it. You don't have to do anything. If you get out of the moldy environment, you don't have to do a thing.”
The EDGE Framework for Longevity With Sandy Martin · 19:58· listen →
“A lot of the harm we're doing to ourselves costs more, right? Like, I'm paying you to poison me. Like, it's just unnecessary to do that.”
The EDGE Framework for Longevity With Sandy Martin · 24:13· listen →
“Every bite we take in can become nutrition for your organs, your tissues, right down to the cell. Or if it's not going to become nutrition because it wasn't nutrient-dense, real food that was properly digested, it will become toxicity. So there isn't really a gray area there.”
Gut Health, Real Food & Detox Truths for Entrepreneurs · 11:16· listen →
“I do not encourage anyone to do any real detoxification without being guided by a professional who knows what they're doing. Because again, we all could have in heavy metals or other things, and if we're not properly set up to prepare for detoxification, we can actually be creating more harm for ourselves.”
Gut Health, Real Food & Detox Truths for Entrepreneurs · 17:24· listen →
Energy and inflammation as the real currency
Multiple guests reframe supplementation and lifestyle work around a single goal: protecting the mitochondrial and nervous-system energy that entrepreneurship burns through.
“Yeah. First of all, if you think about it, if you're out there building a business, you're scaling up, you're doing everything you can. Ultimately, yes, you have a company, you have people that are doing the work, but you're the leader. And leaders spend a lot of energy driving their vision and realization of their vision. So a lot of people think like their greatest assets, it's intelligence, which is true. Their capital, yes, and strategy, no question. But really, your true currency is energy.”
Dr. Mao Shing Ni on Energy, Qi, and Longevity Secrets · 15:35· listen →
“If you have inflammation in your body, you are consuming so much energy. I look at inflammation like a car sitting at an intersection. You've got your foot pedal to the metal. And then so you're revving up to 3,000, 4,000, 5,000 RPMs, but you're not going anywhere. You're just burning fuel. That's what inflammation does.”
Dr. Mao Shing Ni on Energy, Qi, and Longevity Secrets · 17:22· listen →
“You'll notice that your resting heart rate— it's measurable— your resting heart rate will drop by about 10 points after doing 2, 3 minutes of this breathing, which is like amazing if you think about it. It's faster than taking a Xanax.”
Dr. Mao Shing Ni on Energy, Qi, and Longevity Secrets · 33:53· listen →
The companion guide
Reading about supplements & functional mushrooms is one thing. Changing it is another.
John’s companion guide turns what these conversations cover into something you can actually work through.
More moments worth hearing
Everything else these conversations turned up on this subject.
“It's the discipline for the morning routine is easy. The discipline for the evening routine is the one everyone needs to nail.”
Julian Mitchell on Functional Mushrooms & Biohacking · 13:46
“It never makes sense until you look backwards.”
Julian Mitchell on Functional Mushrooms & Biohacking · 28:18
“Why win one prize and then lose 3 others, whether it's your health, relationships, friendships? I'm more of a pro the balanced entrepreneur, not the extreme entrepreneur that burns other boats that are actually really valuable for a meaningful life.”
Julian Mitchell on Functional Mushrooms & Biohacking · 35:37
“Business people is that they get a second chance or a third chance and you can reinvent yourself in your 40s and your 50s and your 60s. As an athlete, you have a finite window.”
Julian Mitchell on Functional Mushrooms & Biohacking · 38:54
“You the entrepreneur, you keep putting the pieces together all by yourself. Maybe you get a third of the way and now you say, hey, how about come and help me now? They still look at the mess. They can see a little bit but nope, they're too busy. Nope.”
Spirulina & Chlorella: The Science of Algae Nutrition · 15:13
“I was driving to work a couple of days ago and I saw a bald eagle and it was sitting at the very top of this very tall tree. And the wind was howling that day. It was just blowing and the snow was blowing and it was just this storm. And this eagle had its face up facing the wind on this, and it was just sitting there letting the storm beat it to death, just perfectly content.”
From Survival to Strength: Breathwork & Resilience · 13:09
“Fight or flight is for we're in danger. Like, fight or flight is tiger chasing me and I'm gonna die. Like, that's what fight or flight is for. Fight or flight is not for everyday living. And that's why we're seeing the high amounts of anxiety.”
From Survival to Strength: Breathwork & Resilience · 16:46
“So somebody honks their horn at you in traffic, you have a test at school that you're stressing out about, you're fighting with your spouse, right? It takes nothing to make that fight-or-flight response go.”
From Survival to Strength: Breathwork & Resilience · 18:26
“My favorite regimen because it's very easy and simple, I have 2 of them that I use in my practice, is the 5-5-7 breathing. And, that's in for 5, hold for 5, out for 7, 3 times, 3 times a day is how I usually start people.”
From Survival to Strength: Breathwork & Resilience · 24:30
“But I thought about that as these women were answering it. And I was like, you know, I am where I am right now. Like, I can't change it. Like, I can't change it. And so I'll say, no, I can't change it. I wouldn't change it.”
From Survival to Strength: Breathwork & Resilience · 39:57
“It said grief is like glitter. And if anybody's had kids or had glitter around, you know what it is, but it's like having glitter all over you and like you clean it up, but it's still in your hair and on your ears and on your skin.”
From Survival to Strength: Breathwork & Resilience · 41:15
“We were sitting at the dining room table, the whole family, my parents, my grandparents, and there was a knocking on the door. We didn't expect anybody, so we didn't open because it was a bad time, you know, these days. And they started knocking louder and kicking, finally kicking with their metal boots in the door that came down. And we knew what was happening then, and they took everybody away.”
From Nazi Orphanage to Vitamin Empire: Charles Van Kessler · 0:49
“All I can tell you is that I still have nightmares 85 years later. My wife keeps waking me up once in a while and I'm just still in the orphanage in my dreams sometimes. Yeah, it's crazy. Crazy.”
From Nazi Orphanage to Vitamin Empire: Charles Van Kessler · 2:33
“It was an incredible undertaking. Incredible. Yeah, I don't know how many times I wanted to quit and just jump in the water, you know, whatever. But I did it. I prayed about it. I did it. And I knew I was close. So Then it came together and my first customer was Regis Philbin.”
From Nazi Orphanage to Vitamin Empire: Charles Van Kessler · 11:05
“We still recently, we paid the mortgage for a whole year for a woman to have 3 kids and the husband died on the way to work. And we read about it and she was disastrously, just, she was going to commit suicide. But then we saved her from that. And then we agreed to give her some money and agreed to pay her mortgage so she and her kids can live, trying to start a new life.”
From Nazi Orphanage to Vitamin Empire: Charles Van Kessler · 11:38
“It's hard work to start a business. It's hard work. You know, you need to be prepared properly and you need to know what you're doing. You need to reach out to the right contacts to help you. And that's what I did.”
From Nazi Orphanage to Vitamin Empire: Charles Van Kessler · 19:04
“Say 1 drink a day, 7 drinks a week. The general consensus that I can see is that that's probably not like really bad, but it certainly is not better than zero.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 5:05
“There are ways to create that sort of social connection of feeling like you're drinking without actually ingesting much... one of my go-to drinks is bitters and soda.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 8:19
“As a human, your number one job in life is to be a professional sleeper... if you can do that, then the idea is you go to bed on time and you wake up when you're done, the same way you go to work on time and you leave work when you're done.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 13:43
“You have 2 women who have 26% body fat. One might have 1 pound of visceral fat, one might have 3 pounds. They're the same weight, the same percent body fat, but the amount of visceral fat they have is dramatically different.”
Longevity As a Competitive Edge: Jesse Levey on Health Strategy · 18:09
Every episode on supplements & functional mushrooms
9 conversations, oldest to newest.
Julian Mitchell on Functional Mushrooms & Biohacking
Mushroom supplement quality varies wildly because many mycelium-based products contain high starch/grain filler, which can be tested at home with an iodine test.
Spirulina & Chlorella: The Science of Algae Nutrition
Spirulina delivers complete amino-acid protein and B vitamins that feed mitochondria, producing steady energy without the crash of stimulants.
From Survival to Strength: Breathwork & Resilience
Chronic fight-or-flight activation undermines decision-making, creativity, and healing, and simple breathing techniques can reliably interrupt it.
From Nazi Orphanage to Vitamin Empire: Charles Van Kessler
Charles survived Nazi persecution, eight years of orphanage abuse, and two years living alone on the streets of Amsterdam before immigrating to America at 22.
Longevity As a Competitive Edge: Jesse Levey on Health Strategy
Most longevity advice is overly individualized or dogmatic, but reducing alcohol and optimizing sleep benefit almost everyone.
Dr. Mao Shing Ni on Energy, Qi, and Longevity Secrets
Energy, not time or intelligence, is the entrepreneur's true currency, produced through mitochondrial ATP, regulated by the nervous system, and channeled as qi in Chinese medicine.
The EDGE Framework for Longevity With Sandy Martin
Toxic mold exposure can cause severe brain dysfunction that mimics other conditions and is often misdiagnosed by conventional doctors.
Gut Health, Real Food & Detox Truths for Entrepreneurs
Gut health underlies nearly every system in the body, from brain function and mood to skin, lungs, and joints, so poor digestion can manifest as brain fog, fatigue, or anxiety.
Jeff Knauss: AI Employees, Bootstrapping & Exit Lessons
AI-powered 'digital employees' can absorb administrative work so humans focus on relationships, decisions, and creative high-value tasks.